Genetic susceptibility to prostate cancer in Taiwan: A genome‐wide association study

• Published in: Molecular carcinogenesis Vol. 63; no. 4; pp. 617 - 628
• Main Authors: Bau, Da‐Tian, Tsai, Chia‐Wen, Chang, Wen‐Shin, Yang, Jai‐Sing, Liu, Ting‐Yuan, Lu, Hsing‐Fang, Wang, Yu‐Wen, Tsai, Fuu‐Jen
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.04.2024
• Subjects: 8q24.21; Carcinogenesis; Chromosome 15; Chromosome 8; CORO2B; genetic risk score; Genetics; Genomes; genome‐wide association study; GRS; lncRNA; Molecular modelling; Non-coding RNA; Prostate cancer; Single-nucleotide polymorphism; SNP; Taiwan; prostate cancer; lncRNA; SNP; genome-wide association study; GRS; genetic risk score; 8q24.21; CORO2B

We conducted the first genome‐wide association study (GWAS) of prostate cancer (PCa) in Taiwan with 1844 cases and 80,709 controls. Thirteen independent single‐nucleotide polymorphisms (SNPs) reached genome‐wide significance (p < 5 × 10−8). Among these, three were distinct from previously identif...