Silibinin affects the pharmacokinetics of methadone in rats - Pan, Pei-Pei; Wang, Jun; Luo, Jun; Wang, Shuang-Hu; Zhou, Yun-Fang; Chen, Sai-Zhen; Du, Zhou (Drug testing and analysis, 2018)
Keywords: Analgesics, Opioid - blood; Analgesics, Opioid - metabolism; Analgesics, Opioid - pharmacokinetics; Animals; Antioxidants - pharmacology; Chromatography, High Pressure Liquid; Male; Methadone - blood; Methadone - metabolism; Methadone - pharmacokinetics; Narcotics - blood; Narcotics - metabolism; Narcotics - pharmacokinetics; Rats, Sprague-Dawley; Silymarin - pharmacology; Tandem Mass Spectrometry; silibinin; pharmacokinetics; methadone