Poor prognosis of ovarian cancer with large cell neuroendocrine carcinoma: Case report and review of published works

• Published in: The journal of obstetrics and gynaecology research Vol. 40; no. 3; pp. 869 - 872
• Main Authors: Asada, Kayo, Kawana, Kei, Teshima, Shinichi, Saito, Ako, Kawabata, Masakiyo, Fujii, Tomoyuki
• Format: Journal Article
• Language: English
• Published: Australia 01.03.2014
• Subjects: Antineoplastic Combined Chemotherapy Protocols - administration & dosage; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Carcinoma, Large Cell - diagnosis; Carcinoma, Large Cell - pathology; Carcinoma, Large Cell - secondary; Carcinoma, Large Cell - therapy; Carcinoma, Neuroendocrine - diagnosis; Carcinoma, Neuroendocrine - drug therapy; Carcinoma, Neuroendocrine - pathology; Carcinoma, Neuroendocrine - surgery; Chemotherapy, Adjuvant; chromogranin A; Drug Resistance, Neoplasm; Fatal Outcome; Female; gynecologic cancer; Humans; Kaplan-Meier Estimate; large cell neuroendocrine carcinoma; Middle Aged; Neoplasm Staging; ovarian cancer; Ovarian Neoplasms - diagnosis; Ovarian Neoplasms - pathology; Ovarian Neoplasms - secondary; Ovarian Neoplasms - therapy; platinum‐based chemotherapy; Prognosis

Large cell neuroendocrine carcinoma (LCNEC) is well‐reported to result in unfavorable prognoses in many organ cancers while being rarely reported in gynecologic cancer, especially ovarian and endometrial cancers. Here we report a case of ovarian cancer with LCNEC which spread to distant organs withi...