Caspase‐driven cancer therapies: Navigating the bridge between lab discoveries and clinical applications

• Published in: Cell biochemistry and function Vol. 42; no. 2; pp. e3944 - n/a
• Main Authors: Allani, Meghana, Akhilesh, Tiwari, Vinod
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.03.2024
• Subjects: Anticancer properties; anticancer therapeutics; Antineoplastic drugs; Apoptosis; cancer; Cancer therapies; Caspase; Cell death; natural compounds; Regulatory mechanisms (biology); synthetic and semisynthetic compounds; natural compounds; apoptosis; cancer; synthetic and semisynthetic compounds; anticancer therapeutics; caspase
• ISSN: 0263-6484; 1099-0844; 1099-0844
• DOI: 10.1002/cbf.3944

Apoptosis is the cell's natural intrinsic regulatory mechanism of normal cells for programmed cell death, which plays an important role in cancer as a classical mechanism of tumor cell death causing minimal inflammation without causing damage to other cells in the vicinity. Induction of apoptos...