Oxidative stress‐A direct bridge to central nervous system homeostatic dysfunction and Alzheimer's disease

• Published in: Cell biochemistry and function Vol. 40; no. 1; pp. 17 - 27
• Main Author: Anwar, Mai M.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.01.2022
• Subjects: Aged; Alzheimer Disease; Alzheimer's disease; Amyloid beta-Peptides - metabolism; Antioxidants; Atrophy; Brain; Brain - metabolism; Cascades; Central nervous system; Cognitive ability; Cytoskeleton; Damage patterns; DAMPs; Fatty acids; Humans; Inflammation; Lipids; Microglia; MSCs; NAC; Nervous system; Neurodegenerative diseases; Oxidative Stress; Polyunsaturated fatty acids; Reactive Oxygen Species; ROS; TLR‐4; NAC; MSCs; TLR-4; ROS; Alzheimer's disease; microglia; oxidative stress; DAMPs

Neurologists have highly observed a frequent increasing number of elderly patients with Alzheimer's disease (AD) without any relevant evidence of any genetic or known AD‐linked predisposing factors in the past few years. Those patients are characterized by continuous and irreversible neuron cel...