A time‐heterogeneous D‐vine copula model for unbalanced and unequally spaced longitudinal data

• Published in: Biometrics Vol. 79; no. 2; pp. 734 - 746
• Main Authors: Hoque, Md Erfanul, Acar, Elif F., Torabi, Mahmoud
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.06.2023
• Subjects: Biostatistics; Computer Simulation; copula; D‐vine; experimental design; Humans; Linear Models; Longitudinal Studies; longitudinal study; Missing data; Models, Statistical; Multivariate analysis; Normal distribution; Performance prediction; Predictive analytics; Research Design; Simulation; Statistical analysis; time‐heterogeneity; trees; vines; time-heterogeneity; D-vine; longitudinal study; copula; missing data

In many longitudinal studies, the number and timing of measurements differ across study subjects. Statistical analysis of such data requires accounting for both the unbalanced study design and the unequal spacing of repeated measurements. This paper proposes a time‐heterogeneous D‐vine copula model...