Ageing and mesenchymal stem cells derived exosomes: Molecular insight and challenges

• Published in: Cell biochemistry and function Vol. 39; no. 1; pp. 60 - 66
• Main Authors: Ahmadi, Mahdi, Rezaie, Jafar
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.01.2021
• Subjects: ageing; Aging; Aging (artificial); Cell death; Degenerative diseases; Exosomes; Homeostasis; Mesenchymal stem cells; Organs; Phenotypes; Regenerative medicine; Risk analysis; Risk factors; Senescence; Stem cells; senescence; ageing; exosomes; mesenchymal stem cells

Ageing induces a great risk factor that participates in progressing various degenerative diseases morbidities. The main characteristic of ageing is the failure in maintaining homeostasis in the organs with a cellular senescence. Senescence is characterized by reduced cell growth, evade cellular deat...