The vitamin D metabolome: An update on analysis and function

• Published in: Cell biochemistry and function Vol. 37; no. 6; pp. 408 - 423
• Main Author: Jenkinson, Carl
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.08.2019
• Subjects: 25-Hydroxyvitamin D; analysis; Animals; Calciferol; conjugation; Humans; Hydroxylase; hydroxylation; Metabolic pathways; Metabolism; Metabolites; Metabolome - physiology; Vitamin D; Vitamin D - analysis; Vitamin D - metabolism; Vitamin D3; metabolism; analysis; hydroxylation; conjugation; vitamin D; metabolic pathways

Current understanding of vitamin D tends to be focussed on the measurement of the major circulating form 25‐hydroxyvitamin D3 (25OHD3) and its conversion to the active hormonal form, 1α,25‐dihydroxyvitamin D3 (1α,25(OH)2D3) via the enzyme 25‐hydroxyvitamin D‐1α‐hydroxylase (CYP27B1). However, whilst...