A review of self-healing hydrogels for bone repair and regeneration: Materials, mechanisms, and applications

• Published in: International journal of biological macromolecules Vol. 287; p. 138323
• Main Authors: Li, Bo, Li, Chenchen, Yan, Ziyi, Yang, Xiaoling, Xiao, Wenqian, Zhang, Dawei, Liu, Zhongning, Liao, Xiaoling
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2025
• Subjects: Animals; biocompatibility; biocompatible materials; Biocompatible Materials - chemistry; Biocompatible Materials - pharmacology; Bone and Bones - drug effects; bone formation; Bone Regeneration - drug effects; Bone repair; bones; Humans; Hydrogel; hydrogels; Hydrogels - chemistry; Hydrogels - pharmacology; Hydrogels - therapeutic use; neoplasms; Osteogenesis - drug effects; resection; Self-healing; Tissue Engineering; tissue repair; Wound Healing - drug effects; Bone repair; Self-healing; Hydrogel

Bone defects, which arise from various factors such as trauma, tumor resection, and infection, present a significant clinical challenge. There is an urgent need to develop new biomaterials capable of repairing a wide array of damage and defects in bone tissue. Self-healing hydrogels, a groundbreakin...