The effects of honey processing on nanoparticles in Astragali Radix decoction: Self-assembly, bioavailability, and bioactivity

• Published in: Food research international Vol. 218; p. 116877
• Main Authors: Zhang, Weiye, Song, Jinjing, Su, Xiao, Zhu, Dandan, Xu, Yan, Jia, Xiaobin, Feng, Liang, Yang, Bing
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.10.2025
• Subjects: Animals; Astragali Radix; Astragalus propinquus; bioactive properties; Bioactivity; Bioavailability; Biological Availability; chemical composition; Drugs, Chinese Herbal - chemistry; Drugs, Chinese Herbal - pharmacokinetics; energy; flavonoids; Flavonoids - analysis; Flavonoids - pharmacokinetics; Food Handling - methods; food research; honey; Honey - analysis; Honey-processing; hydrogen; hydrophobicity; immunomodulators; Intestinal Absorption; Male; medicine; Mice; Nanoparticles; Nanoparticles - chemistry; nutrient uptake; Particle Size; polysaccharides; Polysaccharides - analysis; Rats, Sprague-Dawley; Self-assembly; Nanoparticles; Astragali Radix; Self-assembly; Honey-processing; Bioactivity; Bioavailability; Intestinal absorption

Compared with Astragali Radix (AR), honey-processed Astragali Radix (HAR) exhibits superior efficacy in both Qi-tonifying (enhancement of the body's vital energy to increase fatigue resistance, improve nutrient absorption, and strengthen defenses against illnesses) and immunomodulatory activity...