Closed‐loop parameter optimization for patient‐specific phrenic nerve stimulation

• Published in: Artificial organs Vol. 48; no. 3; pp. 274 - 284
• Main Authors: Keogh, Conor, Saavedra, Francisco, Dubo, Sebastian, Aqueveque, Pablo, Ortega, Paulina, Gomez, Britam, Germany, Enrique, Pinto, Daniela, Osorio, Rodrigo, Pastene, Francisco, Poulton, Adrian, Jarvis, Jonathan, Andrews, Brian, FitzGerald, James J.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.03.2024
• Subjects: Amplitudes; Clinical trials; Diaphragm; Electrical stimuli; Electrodes; Mechanical ventilation; Nerves; Optimization; Parameters; Phrenic nerve; Stimulation; Thresholds; Ventilators; critical care; electrical stimulation; phrenic nerve; ventilator induced diaphragm dysfunction; closed loop

Ventilator-induced diaphragm dysfunction occurs rapidly following the onset of mechanical ventilation and has significant clinical consequences. Phrenic nerve stimulation has shown promise in maintaining diaphragm function by inducing diaphragm contractions. Non-invasive stimulation is an attractive...