Value of Two Noninvasive Methods to Detect Progression of Fibrosis Among HCV Carriers With Normal Aminotransferases

• Published in: Hepatology (Baltimore, Md.) Vol. 42; no. 4; pp. 838 - 845
• Main Authors: Colletta, Cosimo, Smirne, Carlo, Fabris, Carlo, Toniutto, Pierluigi, Rapetti, Rachele, Minisini, Rosalba, Pirisi, Mario
• Format: Journal Article
• Language: English
• Published: Hoboken, NJ Wiley 01.10.2005
• Subjects: Adult; Aged; Alanine Transaminase - blood; Algorithms; Biological and medical sciences; Biomarkers - blood; Biopsy; Carrier State; Disease Progression; Female; Gastroenterology. Liver. Pancreas. Abdomen; Hepatitis C, Chronic - blood; Hepatitis C, Chronic - diagnostic imaging; Hepatitis C, Chronic - pathology; Human viral diseases; Humans; Infectious diseases; Liver Cirrhosis - blood; Liver Cirrhosis - diagnostic imaging; Liver Cirrhosis - pathology; Male; Medical sciences; Middle Aged; Sensitivity and Specificity; Severity of Illness Index; Ultrasonography; Viral diseases; Viral hepatitis; Alanine; Prognosis; Hepatic disease; Histology; Method; Infection; Virus; Biopsy; Aminoacid; Viral disease; Fibrosis; Gastroenterology; Digestive diseases; Evolution; Flaviviridae; Hepatitis C virus; Hepacivirus; Viral hepatitis C

The course of hepatitis C virus (HCV) infection carriers with normal/near-normal aminotransferases (NALT) is usually mild; however, in a few, fibrosis progression occurs. We aimed to verify whether monitoring by liver biopsy might be replaced by noninvasive methods and to identify factors associated...