DNA double-strand break repair in Penaeus monodon is predominantly dependent on homologous recombination

• Published in: DNA research Vol. 24; no. 2; pp. 117 - 128
• Main Authors: Srivastava, Shikha, Dahal, Sumedha, Naidu, Sharanya J, Anand, Deepika, Gopalakrishnan, Vidya, Kooloth Valappil, Rajendran, Raghavan, Sathees C
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.04.2017
• Subjects: Animals; Body Temperature; DNA - metabolism; DNA Breaks, Double-Stranded; DNA End-Joining Repair; Penaeidae - genetics; Penaeidae - physiology; Recombinational DNA Repair; MMEJ; homologous recombination; Double-strand break; Microhomology; Nonhomologous DNA end joining

DNA double-strand breaks (DSBs) are mostly repaired by nonhomologous end joining (NHEJ) and homologous recombination (HR) in higher eukaryotes. In contrast, HR-mediated DSB repair is the major double-strand break repair pathway in lower order organisms such as bacteria and yeast. Penaeus monodon, co...