Preventive effects of taurine against d -galactose-induced cognitive dysfunction and brain damage

• Published in: Food & function Vol. 9; no. 1; pp. 124 - 133
• Main Authors: Tu, Dom-Gene, Chang, Yao-Ling, Chou, Chung-Hsi, Lin, Yi-Ling, Chiang, Chia-Chun, Chang, Yuan-Yen, Chen, Yi-Chen
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 01.01.2018
• Subjects: advanced glycation end products; Advanced glycosylation end products; antioxidant activity; Antioxidants; Apoptosis; Brain; Brain damage; Brain injury; CD11b antigen; cognition; Cognitive ability; D-Galactose; Damage prevention; Degeneration; Dentate gyrus; Galactose; Glial fibrillary acidic protein; Glycosylation; hippocampus; inflammation; Memory; Mice; Neurodegeneration; Neurodegenerative diseases; Oxidative stress; Searching; Shrinkage; Taurine

Oxidative stress arising from life processes or environmental influences and its resultant cellular dysfunctions are major causes of neurodegenerative disorders. The objectives of this study were to investigate whether taurine (Tau) can prevent d -galactose-induced cognitive dysfunction and brain ox...