The crucial role of CTCF in mitotic progression during early development of sea urchin

• Published in: Development, growth & differentiation Vol. 65; no. 7; pp. 395 - 407
• Main Authors: Watanabe, Kaichi, Fujita, Megumi, Okamoto, Kazuko, Yoshioka, Hajime, Moriwaki, Miki, Tagashira, Hideki, Awazu, Akinori, Yamamoto, Takashi, Sakamoto, Naoaki
• Format: Journal Article
• Language: English
• Published: Japan Wiley Subscription Services, Inc 01.09.2023
• Subjects: Blastula; Chromosomes; CRISPR; Developmental stages; Embryogenesis; Embryos; Fusion protein; Genomes; Hemicentrotus pulcherrimus; Histone H3; Histones; Interphase; Mitosis; mRNA; Pluteus; Zinc finger proteins; development; CTCF; sea urchin; mitosis; cell cycle

CCCTC-binding factor (CTCF), an insulator protein with 11 zinc fingers, is enriched at the boundaries of topologically associated domains (TADs) in eukaryotic genomes. In this study, we isolated and analyzed the cDNAs encoding HpCTCF, the CTCF homolog in the sea urchin Hemicentrotus pulcherrimus, to...