The value of urinary exosomal microRNA‐21 in the early diagnosis and prognosis of bladder cancer

• Published in: The Kaohsiung journal of medical sciences Vol. 40; no. 7; pp. 660 - 670
• Main Authors: Yang, Fu‐Kan, Tian, Chao, Zhou, Lin‐Xiong, Guan, Tian‐Yu, Chen, Gui‐Liu, Zheng, Yi‐Ying, Cao, Zheng‐Guo
• Format: Journal Article
• Language: English
• Published: BP, Asia Wiley Publishing Asia Pty Ltd 01.07.2024; John Wiley & Sons, Inc; Wiley
• Subjects: Biomarkers; Biopsy; Bladder cancer; Cellular biology; diagnosis; Independent sample; Males; Metastasis; MicroRNAs; microRNA‐21; prognosis; Proteins; Sample size; Tumors; urinary exosome; Urine; Urogenital system; United Kingdom > UK; China; Germany; microRNA‐21; diagnosis; urinary exosome; prognosis; bladder cancer

Bladder cancer (BC) poses high morbidity and mortality, with urinary exosomal microRNA (miR)‐21 showing potential value in its diagnosis and prognosis, and we probed its specific role. We prospectively selected 116 BC patients and 116 healthy volunteers as the BC and control groups, respectively. BC...