Slow-velocity eccentric-only resistance training improves symptoms of type 2 diabetic mellitus patients by regulating plasma MMP-2 and -9

• Published in: Medicine (Baltimore) Vol. 103; no. 29; p. e38855
• Main Authors: Qian, Zhao, Ping, Liu, Dongming, Xu, Xuelin, Zhang
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 19.07.2024
• Subjects: Adult; Blood Glucose - analysis; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - therapy; Female; Glycated Hemoglobin - analysis; Humans; Insulin - blood; Insulin Resistance - physiology; Male; Matrix Metalloproteinase 2 - blood; Matrix Metalloproteinase 9 - blood; Middle Aged; Muscle Strength - physiology; Resistance Training - methods; type 2 diabetic mellitus; skeletal muscle; extracellular matrix; MMP-2 and -9; eccentric-only resistance training

Objective: This study investigated the intervention effect of slow-velocity eccentric-only resistance training on type 2 diabetic mellitus (T2DM) patients based on the role of matrix metalloproteinase-2 and -9 (MMP-2 and -9) in regulating extracellular matrix homeostasis. Methods: 50 T2DM patients w...