Substance P/calcitonin gene‐related peptide and their receptors expression in human periodontal ligament after root canal preparation with five different systems

• Published in: International endodontic journal Vol. 57; no. 5; pp. 576 - 585
• Main Authors: Caviedes‐Bucheli, Javier, Muñoz‐Alvear, Hernan Dario, Lopez‐Moncayo, Luis Fernando, Kacharaju, Kranthi Raja, Velasquez‐Rivera, Adriana Carolina, Carlosama‐Recalde, Luis Alberto, Pazmiño, Juan Camilo, Gomez‐Sosa, Jose Francisco, Diaz‐Barrera, Luis Eduardo, Munoz, Hugo Roberto
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.05.2024
• Subjects: Calcitonin; Calcitonin gene-related peptide; CGRP receptor 1; Endodontics; human periodontal ligament; instrumentation systems; Ligaments; neurogenic inflammation; Neuropeptides; NK1 receptor; Orthodontics; Peptides; Periodontal ligament; Premolars; Radioimmunoassay; root canal preparation; Root canals; Statistical analysis; Substance P; Teeth; root canal preparation; NK1 receptor; Substance P; instrumentation systems; calcitonin gene-related peptide; CGRP receptor 1; human periodontal ligament; neurogenic inflammation

Aim The purpose of this study was to quantify the effect of five different root canal preparation instruments on Substance P (SP), Calcitonin gene‐related peptide (CGRP) and their receptors expression in healthy human periodontal ligament. Methodology STROBE guidelines were used to design a study us...