Peripheral blood MR1 tetramer‐positive mucosal‐associated invariant T‐cell function is modulated by mammalian target of rapamycin complex 1 in patients with active tuberculosis - Zhou, Chao‐Ying; Yang, Ya‐Long; Han, Zhen‐Yu; Chen, Yao‐Xin; Liu, Hong‐Lin; Fan, Ke; Li, Ming‐Chong; Tu, Si‐Hang; Wen, Qian; Zhou, Xin‐Ying; Ma, Li (Immunology, 2024)
Keywords: Adult; Antigen-presenting cells; Biological effects; Blood; CD4 antigen; CD8 antigen; CD8-Positive T-Lymphocytes - immunology; Cell proliferation; Cytokines - metabolism; Effectiveness; Female; Histocompatibility Antigens Class I - immunology; Histocompatibility Antigens Class I - metabolism; Humans; Immune response; Immune system; Immunotherapy; Invariants; Lymphocyte Activation; Lysis; Male; Mechanistic Target of Rapamycin Complex 1 - metabolism; Middle Aged; Minor Histocompatibility Antigens - immunology; Minor Histocompatibility Antigens - metabolism; MR1 tetramer; mTORC1; Mucosa; Mucosal-Associated Invariant T Cells - immunology; Mucosal-Associated Invariant T Cells - metabolism; mucosal‐associated invariant T cells; Mycobacterium tuberculosis - immunology; Peripheral blood; Population studies; Public health; Rapamycin; Reagents; Sirolimus - pharmacology; Therapeutic targets; TOR protein; Tuberculosis; Tuberculosis - immunology; Vaccine efficacy; Young Adult; mucosal‐associated invariant T cells; MR1 tetramer; mTORC1; tuberculosis