O6-Alkylguanine DNA alkyltransferase activity in student embalmers

• Published in: American journal of industrial medicine Vol. 31; no. 3; pp. 361 - 365
• Main Authors: Hayes, Richard B., Klein, Sonja, Suruda, Anthony, Schulte, Paul, Boeniger, Mark, Stewart, Patricia, Livingston, Gordon K., Oesch, Franz
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 01.03.1997; Wiley-Liss
• Subjects: Adult; Air Pollutants, Occupational - adverse effects; Air Pollutants, Occupational - analysis; Biological and medical sciences; Chemical and industrial products toxicology. Toxic occupational diseases; DNA repair; DNA Repair - drug effects; Embalming; Female; formaldehyde; Formaldehyde - adverse effects; Formaldehyde - analysis; Humans; Lymphocytes - enzymology; Male; Medical sciences; Methyltransferases - drug effects; Methyltransferases - metabolism; O-Methylguanine-DNA Methyltransferase; occupational exposure; Occupational Exposure - adverse effects; Occupational Exposure - analysis; Toxicology; Various organic compounds; Human; Biological fluid; Enzyme; Toxicity; Transferases; Biological marker; Student; Occupational exposure; Formaldehyde; Blood; Biological monitoring; Carcinogen; Methylated-DNA-protein-cysteine S-methyltransferase; Methyltransferases; DNA; Lymphocyte; Occupational medicine

O6‐Alkylguanine‐DNA alkyltransferase (AGT) activity was assessed in peripheral blood lymphocytes among 23 mortuary science students before and after 9 weeks in a laboratory course in techniques of embalming. Formaldehyde exposure was established by environmental monitoring. The average air concentra...