Detection of brain amyloid‐β deposits due to the repetitive head trauma in a former karate player

• Published in: Psychogeriatrics Vol. 19; no. 3; pp. 276 - 281
• Main Authors: Takahashi, Masato, Yasuno, Fumihiko, Yamamuro, Kazuhiko, Matsuoka, Kiwamu, Kitamura, Soichiro, Yoshikawa, Hiroaki, Yamamoto, Akihide, Iida, Hidehiro, Fukuda, Tetsuya, Ihara, Masafumi, Nagatsuka, Kazuyuki, Kishimoto, Toshifumi
• Format: Journal Article
• Language: English
• Published: Melbourne John Wiley & Sons Australia, Ltd 01.05.2019; Blackwell Publishing Ltd
• Subjects: 11C‐labelled Pittsburgh compound B; Alzheimer's disease; amyloid deposition; Cerebellum; Cognitive ability; cognitive deterioration; Cortex (frontal); Cortex (temporal); Epidemiology; Geriatrics; Head; Head injuries; Magnetic resonance imaging; Medical imaging; Neurodegenerative diseases; Neuroimaging; NMR; Nuclear magnetic resonance; Positron emission tomography; Prefrontal cortex; Substantia grisea; Tau protein; Tomography; Trauma; traumatic brain injury; United States > US; Pittsburgh Pennsylvania; cognitive deterioration; traumatic brain injury; positron emission tomography; amyloid deposition; 11C-labelled Pittsburgh compound B

Head trauma is a well‐established epidemiological risk factor for Alzheimer's disease, but a study of early detection of its pathology has not yet been performed in human patients in vivo. To address this issue, we performed 11C‐labelled Pittsburgh compound B‐positron emission tomography on a r...