RETRACTED: Resveratrol Inhibits the Migration and Metastasis of MDA-MB-231 Human Breast Cancer by Reversing TGF-β1-Induced Epithelial-Mesenchymal Transition

• Published in: Molecules (Basel, Switzerland) Vol. 24; no. 6; p. 1131
• Main Authors: Sun, Yang, Zhou, Qian-Mei, Lu, Yi-Yu, Zhang, Hui, Chen, Qi-Long, Zhao, Ming, Su, Shi-Bing
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.03.2019
• Subjects: Animals; Breast cancer; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Cancer; Cell adhesion & migration; Cell growth; Cell Line, Tumor; Cell Movement - drug effects; Cell Survival - drug effects; Cytoskeleton; Disease Models, Animal; EMT; Enzyme-linked immunosorbent assay; Enzymes; Epithelial-Mesenchymal Transition - drug effects; Female; Genotype & phenotype; Growth factors; Humans; Kinases; Liver cancer; Lung cancer; Matrix Metalloproteinases - metabolism; MDA-MB-231 cell; Medical prognosis; Metastasis; Mice; migration; Morphology; Phosphatidylinositol 3-Kinases - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Resveratrol; Resveratrol - pharmacology; Signal Transduction - drug effects; Smad Proteins - metabolism; Stem cells; Transforming Growth Factor beta1 - metabolism; Transforming Growth Factor beta1 - pharmacology; Transforming growth factors; Tumors; Xenograft Model Antitumor Assays; United States; China; MDA-MB-231 cell; migration; breast cancer; metastasis; EMT; resveratrol

Metastasis is a major cause of death in patients with breast cancer. In the process of cancer development, epithelial-mesenchymal transition (EMT) is crucial to promoting the invasion and migration of tumor cells. In a previous study, the role of resveratrol in migration and metastasis was investiga...