Ritonavir May Prolong Sedation but is Unlikely to Increase the Risk of Respiratory Arrest in Patients Requiring Intravenous Midazolam for Procedural Sedation - Arsanious, Jason; Rowland, Angela; Sorich, Michael J; Hopkins, Ashley M; Alfred, Sam; Rowland, Andrew (Journal of clinical pharmacology, 2025)
Keywords: Adult; Area Under Curve; Drug Interactions; Female; Humans; Hypnotics and Sedatives - administration & dosage; Hypnotics and Sedatives - adverse effects; Hypnotics and Sedatives - pharmacokinetics; Male; Midazolam - administration & dosage; Midazolam - adverse effects; Midazolam - pharmacokinetics; Middle Aged; Models, Biological; Ritonavir - administration & dosage; Ritonavir - adverse effects; Ritonavir - pharmacokinetics; Ritonavir - pharmacology; Young Adult; toxicity; procedural sedation; midazolam; drug interaction; ritonavir