Association between plasminogen activator inhibitor‑1 (PAI-1) 4G/5G polymorphism and circulating PAI-1 level in systemic lupus erythematosus and rheumatoid arthritis A meta-analysis

• Published in: Zeitschrift für Rheumatologie Vol. 79; no. 3; pp. 312 - 318
• Main Authors: Bae, S.-C., Lee, Y. H.
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer Medizin 01.04.2020
• Subjects: Arthritis, Rheumatoid - genetics; Genetic Predisposition to Disease; Humans; Immunology; Internal Medicine; Laboratory Medicine; Lupus Erythematosus, Systemic - genetics; Medicine; Medicine & Public Health; Originalien; Orthopedics; Plasminogen; Plasminogen Activator Inhibitor 1 - genetics; Polymorphism, Genetic - genetics; Rheumatology; Genetischer Polymorphismus; Matrix metalloproteinases; Autoimmunerkrankungen; Polymorphism, genetic; Serine proteinase inhibitors; Case-control studies; Fall-Kontroll-Studien; Autoimmune diseases; Matrixmetalloproteinasen; Serinproteinaseinhibitoren

Objective This study systemically reviewed the evidence regarding the association between plasminogen activator inhibitor‑1 ( PAI‑1 ) 4G/5G polymorphism and susceptibility to systemic lupus erythematous (SLE)/lupus nephritis (LN) and rheumatoid arthritis (RA) and the relationship between circulating...