Reduction of insulin resistance by combined kidney-pancreas transplantation in type 1 (insulin-dependent) diabetic patients

• Published in: Diabetologia Vol. 33; no. 9; p. 549
• Main Authors: Luzi, L, Secchi, A, Facchini, F, Battezzati, A, Staudacher, C, Spotti, D, Castoldi, R, Ferrari, G, Di Carlo, V, Pozza, G
• Format: Journal Article
• Language: English
• Published: Germany 01.09.1990
• Subjects: Adult; Blood Glucose - metabolism; Blood Pressure; Diabetes Mellitus, Type 1 - drug therapy; Diabetes Mellitus, Type 1 - physiopathology; Diabetes Mellitus, Type 1 - surgery; Fatty Acids, Nonesterified - blood; Female; Glucagon - blood; Glucose - metabolism; Glycated Hemoglobin A - analysis; Humans; Insulin - blood; Insulin Infusion Systems; Insulin Resistance; Kidney Failure, Chronic - surgery; Kidney Transplantation - physiology; Male; Pancreas Transplantation - physiology; Reference Values

To evaluate the effect of combined kidney and pancreas transplantation on insulin action and glucose metabolism, 15 Type 1 (insulin-dependent) diabetic patients who were undergoing combined kidney-pancreas transplantation were studied before transplantation by means of the euglycaemic hyperinsulinae...