Successful management with Janus kinase inhibitor tofacitinib in refractory juvenile dermatomyositis: a pilot study and literature review

• Published in: Rheumatology (Oxford, England) Vol. 60; no. 4; pp. 1700 - 1707
• Main Authors: Yu, Zhongxun, Wang, Lin, Quan, Meiying, Zhang, Tiannan, Song, Hongmei
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 06.04.2021
• Subjects: JDM; efficacy; tofacitinib

Abstract Objectives JDM is a rare autoimmune inflammatory muscle disease with a pronounced IFN signature. Treatment for children with JDM has improved over the years with the use of steroids and immunosuppressive agents. However, there remains a subset of children who have refractory disease. Janus...