Characterizing scientific failure Putting the replication crisis in context

Graphical Abstract A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical research.

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Published inEMBO reports Vol. 20; no. 9; p. e48765
Main Authors Guttinger, Stephan, Love, Alan C
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.09.2019
John Wiley and Sons Inc
Subjects
Biomedical Research - standards
EMBO47
EMBO53
Humans
Publishing
Science & Society
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Abstract Graphical Abstract A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical research.
AbstractList A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical research.
Graphical Abstract A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical research.
A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical research.A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical research.
Author Guttinger, Stephan
Love, Alan C
AuthorAffiliation 2 Department of Philosophy University of Minnesota Minneapolis MN USA
3 Minnesota Center for Philosophy of Science University of Minnesota Minneapolis MN USA
1 Center for Philosophy of Natural and Social Science London School of Economics London UK
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Cites_doi 10.1038/s41562-016-0021
10.1177/0956797611430953
10.1038/d41586-018-01023-3
10.1086/684960
10.1073/pnas.1806370115
10.3389/fmolb.2018.00083
10.1038/497433a
10.1002/bies.201800055
10.1074/jbc.R115.685859
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References RedishADKummerfeldEMorrisRLLoveACOpinion: Reproducibility failures are essential to scientific inquiryProc Natl Acad Sci USA201811550425046
JohnLKLoewensteinGPrelecDMeasuring the prevalence of questionable research practices with incentives for truth tellingPsychol Sci201223524532
MunafòMRSmithGDRepeating experiments is not enoughNature2018553399401
MunafòMRNosekBABishopDVMButtonKSChambersCDPercie du SertNSimonsohnUWagenmakersE‐JWareJJIoannidisJPAA manifesto for reproducible scienceNat Hum Behav201710021
BegleyCGReproducibility: six red flags for suspect workNature2013497433434
GuttingerSReplications everywhere: why the replication crisis might be less severe than it seems at firstBioEssays201840e1800055
Contreras MartosSNguyenHNNguyenPNHristozovaNMacossay‐CastilloMKovacsDBekesiAOemigJSMaesDPauwelsKQuantification of intrinsically disordered proteins: a problem not fully appreciatedFront Mol Biosci2018583
KuorikoskiJMarchionniCEvidential diversity and the triangulation of phenomenaPhilos Sci201683227247
FiresteinSFailure: why science is so successful2015OxfordOxford University Press
UverskyVNDancing protein clouds: the strange biology and chaotic physics of intrinsically disordered proteinsJ Biol Chem201629166816688
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Snippet Graphical Abstract A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical...
A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical research.
A better understanding of the nature and causes of failure in research could inform policies to improve the reproducibility of biomedical research.A better...
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SubjectTerms Biomedical Research - standards
EMBO47
EMBO53
Humans
Publishing
Science & Society
Subtitle Putting the replication crisis in context
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Title Characterizing scientific failure
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