Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N -glycan modulators as anticancer agents - Chen, Wei-An; Chen, Yu-Hsin; Hsieh, Chiao-Yun; Hung, Pi-Fang; Chen, Chiao-Wen; Chen, Chien-Hung; Lin, Jung-Lee; Cheng, Ting-Jen R.; Hsu, Tsui-Ling; Wu, Ying-Ta; Shen, Chia-Ning; Cheng, Wei-Chieh (Chemical science (Cambridge), 2022)
Keywords: Anticancer properties; Cancer; Chemical synthesis; Chemistry; Chemistry, Multidisciplinary; Combinatorial analysis; Combinatorial chemistry; Computation; Glycan; In vivo methods and tests; Inhibitors; Modulation; Modulators; Natural products; Physical Sciences; Science & Technology; Selectivity; 5-SUBSTITUTED SWAINSONINE ANALOGS; SELECTIVE INHIBITORS; MECHANISMS; GLYCOSYLATION; SCAFFOLDS; ALPHA-MANNOSIDASE-II; CANCER