Profiles of surface mosaics on chronic lymphocytic leukemias distinguish stable and progressive subtypes

• Published in: Journal of pharmacy & pharmaceutical sciences Vol. 16; no. 2; pp. 231 - 237
• Main Authors: Huang, Pauline Y, Kohnke, Philippa, Belov, Larissa, Best, O Giles, Mulligan, Stephen Peter, Christopherson, Richard I
• Format: Journal Article
• Language: English
• Published: Canada Frontiers Media S.A 01.01.2013
• Subjects: Antibodies - immunology; Antigens, CD - immunology; Disease Progression; Humans; Leukemia, Lymphocytic, Chronic, B-Cell - immunology; Microarray Analysis

Chronic lymphocytic leukemia (CLL) is a heterogeneous disease, some patients may survive for many years, while 20-30% of patients progress and may die within several years. Currently, there is not a single procedure that enables accurate prognosis and triaging of those patients who need immediate an...