Emerging therapies in cancer metabolism

• Published in: Cell metabolism Vol. 35; no. 8; pp. 1283 - 1303
• Main Authors: Xiao, Yi, Yu, Tian-Jian, Xu, Ying, Ding, Rui, Wang, Yi-Ping, Jiang, Yi-Zhou, Shao, Zhi-Ming
• Format: Journal Article
• Language: English
• Published: United States 08.08.2023
• Subjects: Humans; Metabolic Networks and Pathways; Neoplasms - metabolism

Metabolic reprogramming in cancer is not only a biological hallmark but also reveals treatment vulnerabilities. Numerous metabolic molecules have shown promise as treatment targets to impede tumor progression in preclinical studies, with some advancing to clinical trials. However, the intricacy and...