Combination of calcineurin and mTOR inhibitors in kidney transplantation: a propensity score analysis based on current clinical practice

• Published in: Journal of nephrology Vol. 33; no. 3; pp. 601 - 610
• Main Authors: Cucchiari, David, Ríos, José, Molina-Andujar, Alicia, Montagud-Marrahi, Enrique, Revuelta, Ignacio, Ventura-Aguiar, Pedro, Piñeiro, Gastón J., De Sousa-Amorim, Erika, Esforzado, Nuria, Cofán, Frederic, Torregrosa, Jose-Vicente, Ugalde-Altamirano, Jessica, Ricart, Maria José, Rovira, Jordi, Torres, Ferran, Solè, Manel, Campistol, Josep M., Diekmann, Fritz, Oppenheimer, Frederic
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.06.2020
• Subjects: Medicine; Medicine & Public Health; Nephrology; Original Article; Urology; Rejection; mTOR inhibitors; Propensity score; Survival; Kidney transplantation

Introduction The TRANSFORM study demonstrated that an immunosuppression based on a combination of calcineurin inhibitors and de-novo mTOR inhibitors (mTORi) is safe and effective in kidney transplant recipients. However, data that validate this approach in clinical practice are currently missing. Ma...