Visible light driven, nickel-catalyzed aryl esterification using a triplet photosensitiser thioxanthen-9-one

• Published in: ORGANIC CHEMISTRY FRONTIERS Vol. 6; no. 14; pp. 2353 - 2359
• Main Authors: Zhu, Da-Liang, Li, Hong-Xi, Xu, Ze-Ming, Li, Hai-Yan, Young, David J., Lang, Jian-Ping
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 2019; Royal Society of Chemistry
• Subjects: Aromatic compounds; Bromides; Carboxylic acids; Chemistry; Chemistry, Organic; Cross coupling; Energy transfer; Esterification; Esters; Ketones; Nickel; NMR; Nuclear magnetic resonance; Organic chemistry; Photochemicals; Physical Sciences; Science & Technology; METAL-FREE SYNTHESIS; ACTIVATION; 2+2 PHOTOCYCLOADDITION; ESTERS; COMPLEXES; ARYLATION; CARBOXYLIC-ACIDS; PHOTOREDOX CATALYSIS; TRIFLUOROMETHYLATION

We report an approach to the visible light-initiated, nickel-catalyzed esterification of carboxylic acids with aryl bromides. Thioxanthen-9-one works as a triplet photosensitizer to significantly accelerate this cross-coupling to provide aryl esters in moderate to excellent yields at room temperatur...