Targeting cytokines and signaling molecules related to immune pathways in atopic dermatitis: therapeutic implications and challenges

• Published in: Archives of pharmacal research Vol. 45; no. 12; pp. 894 - 908
• Main Author: Kim, Hyung-Ook
• Format: Journal Article
• Language: English
• Published: Seoul Pharmaceutical Society of Korea 01.12.2022
• Subjects: Medicine; Pharmacology/Toxicology; Pharmacy; Review; Th1 pathways, Targeted therapeutics, Therapeutic implications; Th22; Atopic dermatitis, Th2; Th17

Although atopic dermatitis (AD) is primarily a Th2-driven disease, it shows high heterogeneity with additional variable contributions of the Th22, Th17, and Th1 pathways, depending on the subtype of the disease. Expanding knowledge and understanding of AD pathogenesis has promoted the development of...