Identification of serum miR-34a as a potential biomarker in acute myeloid leukemia

• Published in: Cancer biomarkers : section A of Disease markers Vol. 22; no. 4; pp. 799 - 805
• Main Authors: Huang, Yiqun, Zou, Yong, Lin, Luhui, Ma, Xudong, Chen, Hongpu
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.01.2018; Sage Publications Ltd
• Subjects: Acute myeloid leukemia; Apoptosis; Biomarkers; Cytogenetics; Diagnostic software; Diagnostic systems; Leukemia; Medical prognosis; miRNA; Myeloid leukemia; Patients; Ribonucleic acid; RNA; diagnosis; acute myeloid leukemia; biomarker; miR-34a; prognosis

BACKGROUND: MicroRNA-34a (miR-34a), as a tumor-suppressive miRNA, has been found to induce cell apoptosis in acute myeloid leukemia (AML). However, the diagnostic and prognostic significance of miR-34a in AML remains largely unknown. OBJECTIVE: We aimed to explore its associations with clinical char...