In vitro biodegradability of Mg–2Gd–xZn alloys with different Zn contents and solution treatments

• Published in: Rare metals Vol. 38; no. 7; pp. 620 - 628
• Main Authors: Zhang, Meng, Deng, Wei-Lin, Yang, Xiao-Ning, Wang, Yong-Kang, Zhang, Xiang-Yu, Hang, Rui-Qiang, Deng, Kun-Kun, Huang, Xiao-Bo
• Format: Journal Article
• Language: English
• Published: Beijing Nonferrous Metals Society of China 10.07.2019; Springer Nature B.V
• Subjects: Alloy development; Binary alloys; Biocompatibility; Biodegradability; Biomaterials; Chemistry and Materials Science; Corrosion; Corrosion rate; Corrosion resistance; Corrosion resistant alloys; Energy; Grain size; Intermetallic phases; Magnesium; Materials Engineering; Materials Science; Metallic Materials; Nanoscale Science and Technology; Permanent mold casting; Permanent molds; Physical Chemistry; Solution heat treatment; Surgical implants; Ternary alloys; Ternary systems; Zinc; Corrosion resistance; Mg–2Gd; Zn; Cytocompatibility; Biodegradability
• ISSN: 1001-0521; 1867-7185
• DOI: 10.1007/s12598-019-01220-7

This study aims to investigate the addition of Zn on the corrosion property and cytocompatibility of Mg–2Gd– x Zn ( x  = 0, 3, 4 and 5; wt%) alloys, which were prepared by gravity permanent mold casting and solution treatment, respectively. The results show that the intermetallic phases of these ternary alloys are mainly composed of Mg 12 GdZn and Mg 3 GdZn 3 . The content of secondary phases as well as the grain size is greatly dependent on the Zn addition. Compared to the binary Mg–2Gd alloy, the corrosion resistance of the most ternary alloys is significantly improved. Furthermore, the in vitro cell culture study demonstrates the potential cytocompatibility of the developed ternary alloys. It indicates that a series of Mg–2Gd– x Zn ( x  = 0, 3, 4 and 5; wt%) with medically acceptable corrosion rate are developed and show great potential use as a new type of biodegradable implants.