MicroRNAs in contusion spinal cord injury: pathophysiology and clinical utility

• Published in: Acta neurologica Belgica Vol. 119; no. 1; pp. 21 - 27
• Main Authors: Li, Fang, Zhou, Mou-Wang
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.03.2019
• Subjects: Biomedical and Life Sciences; Biomedicine; Medicine/Public Health; Neurology; Neuroradiology; Neurosciences; Review Article; Spinal cord injury; MicroRNAs; Review

Spinal cord injury (SCI) in humans is a common central nervous system trauma. Pathophysiologically, SCI involves both primary and secondary damages. Therapeutically, targeting secondary damage including inflammation, neuropathic pain, apoptosis, demyelination, and glial reaction to promote functiona...