A Novel Two-Compartment Model for Calculating Bone Volume Fractions and Bone Mineral Densities From Computed Tomography Images

• Published in: IEEE transactions on medical imaging Vol. 36; no. 5; pp. 1094 - 1105
• Main Authors: Hsin-Hon Lin, Shin-Lei Peng, Wu, Jay, Tian-Yu Shih, Keh-Shih Chuang, Cheng-Ting Shih
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.05.2017; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: 3D-printed trabecular structural phantom; Absorptiometry, Photon; Attenuation; Biocompatibility; Biomedical materials; Bone and Bones; Bone Density; bone equivalent uniform phantom; Bone mineral density; Bone tissue; bone volume fraction; Bones; Computation; Computed tomography; Dual energy X-ray absorptiometry; Energy measurement; Equivalence; Humans; Image contrast; Image processing; Image segmentation; lumbar vertebra; Mathematical models; Measurement methods; Medical imaging; Osteoporosis; partial volume effect; Phantoms; Temporal bone; Three dimensional printing; Tomography; Tomography, X-Ray Computed; Vertebrae

Osteoporosis is a disease characterized by a degradation of bone structures. Various methods have been developed to diagnose osteoporosis by measuring bone mineral density (BMD) of patients. However, BMDs from these methods were not equivalent and were incomparable. In addition, partial volume effec...