Giant skull vault defect in a child caused by Langerhans cell histiocytosis: the “calvaria-eating disease”

• Published in: Child's nervous system Vol. 36; no. 3; pp. 651 - 654
• Main Authors: Gosal, Jaskaran Singh, Ruparelia, Jigish, Garg, Mayank, Praneeth, Kokkula, Bhaskar, Suryanarayanan, Jha, Deepak Kumar
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2020
• Subjects: Bone Cements; Case Report; Child, Preschool; Histiocytosis, Langerhans-Cell - complications; Histiocytosis, Langerhans-Cell - diagnostic imaging; Histiocytosis, Langerhans-Cell - surgery; Humans; Male; Medicine; Medicine & Public Health; Neurosciences; Neurosurgery; Polymethyl Methacrylate; Skull - diagnostic imaging; Skull - surgery; Surgical Flaps; Cranioplasty; Giant calvarial defect; Langerhans cell histiocytosis; Polymethyl methacrylate

Langerhans cell histiocytosis (LCH) is a rare disease of young children that can be difficult to diagnose and treat. Clinical manifestations can sometimes be quite unusual, and bony lesions can reach a large size before treatment is sought. We present a unique case of a 3-year-old male child with a...