Endothelial vasomotor regulation in health and disease

• Published in: Canadian journal of anesthesia Vol. 39; no. 8; pp. 838 - 857
• Main Authors: SEARLE, N. R, SAHAB
• Format: Journal Article
• Language: English
• Published: Toronto, ON Canadian Anesthesiologists' Society 01.10.1992
• Subjects: Anesthetics - pharmacology; Biological and medical sciences; Blood vessels and receptors; Disease; Endothelium, Vascular - physiology; Fundamental and applied biological sciences. Psychology; Health; Humans; Nitric Oxide - pharmacology; Nitric Oxide - physiology; Vasomotor System - physiology; Vertebrates: cardiovascular system; Vasomotricity; General anesthetic; Pathophysiology; Blood vessel; Nitrogen monoxide; Circulatory system; Review; Endothelium derived relaxing factor; Hemodynamics; Endothelium

The purpose of this review is to provide the anaesthetists with a comprehensive update on the endothelial-cell control of local blood flow. This single cell layer was originally thought to represent only a passive barrier. It is now evident that it plays an active role in a broad variety of biologic...