Detection of reactive oxygen species in the skin of live mice and rats exposed to UVA light: a research review on chemiluminescence and trials for UVA protection

• Published in: Photochemical & photobiological sciences Vol. 4; no. 9; pp. 715 - 720
• Main Authors: Sakurai, Hiromu, Yasui, Hiroyuki, Yamada, Yumiko, Nishimura, Hitoshi, Shigemoto, Mariko
• Format: Journal Article
• Language: English
• Published: England 01.09.2005
• Subjects: Animals; Antioxidants - pharmacology; Luminescent Measurements; Mice; Oils, Volatile - pharmacology; Rats; Reactive Oxygen Species - metabolism; Skin - metabolism; Skin - radiation effects; Skin Aging - radiation effects; Sunscreening Agents - pharmacology; Ultraviolet Rays - adverse effects

The harmful effects of ultraviolet (UV) exposure on the skin are associated with the generation of reactive oxygen species (ROS) such as superoxide anion radical ( O(2)(-)), hydrogen peroxide (H(2)O(2)), hydroxyl radical ( OH), and singlet oxygen ((1)O(2)) as well as with lipid peroxides and their r...