Pgp-mediated interaction between (R)-[11C]verapamil and tariquidar at the human blood-brain barrier: a comparison with rat data - Bauer, M; Zeitlinger, M; Karch, R; Matzneller, P; Stanek, J; Jäger, W; Böhmdorfer, M; Wadsak, W; Mitterhauser, M; Bankstahl, J P; Löscher, W; Koepp, M; et al. (Clinical pharmacology and therapeutics, 2012)
Keywords: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors; Blood-Brain Barrier - diagnostic imaging; Blood-Brain Barrier - drug effects; Brain - diagnostic imaging; Brain - metabolism; Calcium Channel Blockers - pharmacology; Carbon Radioisotopes; Dose-Response Relationship, Drug; Humans; Positron-Emission Tomography - methods; Positron-Emission Tomography - statistics & numerical data; Quinolines - blood; Quinolines - pharmacology; Rats; Species Specificity; Verapamil - pharmacokinetics