Maternal exposure to chronic, low-dose nonylphenol in zebrafish: Disruption of ovarian health, reproductive function, and embryogenesis

• Published in: Journal of environmental management Vol. 375; p. 124169
• Main Authors: Samanta, Anwesha, Biswas, Subhasri, Ghosh, Sandip, Banerjee, Sambuddha, Dam, Bomba, Maitra, Sudipta
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2025
• Subjects: Animals; apoptosis; aromatase; caspase-3; computer simulation; Danio rerio; embryogenesis; Embryonic development; Embryonic Development - drug effects; embryotoxicity; Endocrine Disruptors - toxicity; endocrine-disrupting chemicals; environmental fate; environmental management; Estrogen receptor (ER); fecundity; Female; female fertility; follicular atresia; Inflammation; interleukin-6; Maternal Exposure; mitogen-activated protein kinase; muscle tissues; nonionic surfactants; Nonylphenol; nonylphenols; Oocyte maturation; oocytes; Ovary; Ovary - drug effects; Phenols - toxicity; progeny; prostaglandin synthase; reactive oxygen species; Reproduction - drug effects; Zebrafish; Ovary; Embryonic development; Estrogen receptor (ER); Danio rerio; Inflammation; Nonylphenol; Oocyte maturation

Nonylphenol (NP), a non-ionic surfactant and potent endocrine disruptor, is known for its environmental persistence, biotic accumulation potential and toxicity. Nonetheless, mechanisms underlying NP modulation of female fertility with potential impact on embryogenesis in the unexposed offspring rema...