Preliminary study on the production of transgenic mice harboring hepatitis B virus X gene

• Published in: World journal of gastroenterology : WJG Vol. 4; no. 6; pp. 536 - 539
• Main Authors: Zhu, Huan-Zhang, Cheng, Guo-Xiang, Chen, Jian-Qu, Kuang, Shu-Yuan, Cheng, Yong, Zhang, Xin-Li, Li, Hou-Da, Xu, Shao-Fu, Shi, Jing-Quan, Qian, Geng-Sun, Gu, Jian-Ren
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 01.12.1998
• Subjects: Original

AIM:To establish transgenic mice lineage harboring hepatitis B virus X gene and to provide an efficient animal model for studying the exact role of the HBx gene in the process of hepatocarcinogenesis.METHODS:The HBx transgenic mice were produced by microinjecting the construct with X gene of HBV (su...