Antipsychotic prescribing patterns, and the factors and outcomes associated with their use, among patients requiring prolonged mechanical ventilation in the long-term acute care hospital setting

• Published in: The Annals of pharmacotherapy Vol. 47; no. 2; p. 181
• Main Authors: Al-Qadheeb, Nada S, O'Connor, Heidi H, White, Alexander C, Neidhardt, Aura, Albizati, Mark, Joseph, Bernard, Roberts, Russel J, Ruthazer, Robin R, Devlin, John W
• Format: Journal Article
• Language: English
• Published: United States 01.02.2013
• Subjects: Adult; Aged; Aged, 80 and over; Antipsychotic Agents - administration & dosage; Antipsychotic Agents - adverse effects; Antipsychotic Agents - therapeutic use; Benzodiazepines - administration & dosage; Benzodiazepines - adverse effects; Benzodiazepines - therapeutic use; Caregivers; Cohort Studies; Delirium - diagnosis; Delirium - drug therapy; Delirium - physiopathology; Delirium - prevention & control; Dibenzothiazepines - administration & dosage; Dibenzothiazepines - adverse effects; Dibenzothiazepines - therapeutic use; Drug Administration Schedule; Female; Hospitals, Chronic Disease; Humans; Male; Massachusetts; Medical Records; Middle Aged; Patient Participation; Practice Patterns, Physicians; Psychiatric Status Rating Scales; Quetiapine Fumarate; Respiration, Artificial - psychology; Retrospective Studies; Massachusetts

Administration of scheduled antipsychotic therapy to mechanically ventilated patients to prevent or treat delirium is common, despite the lack of evidence to support its use. Among long-term acute care hospital (LTACH) patients requiring prolonged mechanical ventilation (PMV), the frequency of sched...