Prolonged stable hypothermia: effect on blood gases and pH in rats and ground squirrels

• Published in: The American journal of physiology Vol. 262; no. 2 Pt 2; p. R190
• Main Authors: McArthur, M D, Jourdan, M L, Wang, L C
• Format: Journal Article
• Language: English
• Published: United States 01.02.1992
• Subjects: Animals; Carbon Dioxide - blood; Hematocrit; Hydrogen-Ion Concentration; Hypothermia - blood; Hypothermia - metabolism; Lactates - blood; Lactic Acid; Male; Osmolar Concentration; Oxygen - blood; Rats; Rats, Inbred Strains; Sciuridae

Richardson's ground squirrels [body temperature (Tb) 7 degrees C] survive prolonged stable hypothermia for three times as long as do rats (Tb 19 degrees C) (72 vs. 24 h). We have examined the changes in blood gases and acid-base state to assess whether these contribute to this difference in sur...