Survival in Patients With Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension in the Modern Management Era

• Published in: Circulation (New York, N.Y.) Vol. 122; no. 2; pp. 156 - 163
• Main Authors: Humbert, Marc, Sitbon, Olivier, Chaouat, Ari, Bertocchi, Michèle, Habib, Gilbert, Gressin, Virginie, Yaïci, Azzedine, Weitzenblum, Emmanuel, Cordier, Jean-François, Chabot, François, Dromer, Claire, Pison, Christophe, Reynaud-Gaubert, Martine, Haloun, Alain, Laurent, Marcel, Hachulla, Eric, Cottin, Vincent, Degano, Bruno, Jaïs, Xavier, Montani, David, Souza, Rogério, Simonneau, Gérald
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 13.07.2010
• Subjects: Adult; Aged; Biological and medical sciences; Blood and lymphatic vessels; Cardiac Output; Cardiology. Vascular system; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Female; Follow-Up Studies; Genetic Diseases, Inborn - drug therapy; Genetic Diseases, Inborn - mortality; Genetic Diseases, Inborn - physiopathology; Humans; Hypertension, Pulmonary - drug therapy; Hypertension, Pulmonary - mortality; Hypertension, Pulmonary - physiopathology; In Vitro Techniques; Incidence; Male; Medical sciences; Middle Aged; Pneumology; Prevalence; Prospective Studies; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases; Sex Factors; Survival Rate; Physical exercise; Human; Hypertension; risk factors; Respiratory disease; Mortality; Idiopathic; sex; Cardiovascular disease; exercise; pulmonary; Survival; Pulmonary hypertension; Clinical management; Risk factor

Background— Novel therapies have recently become available for pulmonary arterial hypertension. We conducted a study to characterize mortality in a multicenter prospective cohort of patients diagnosed with idiopathic, familial, or anorexigen-associated pulmonary arterial hypertension in the modern m...