Role of glycogen in control of glycolysis and IMP formation in human muscle during exercise

• Published in: The American journal of physiology Vol. 260; no. 6 Pt 1; p. E859
• Main Authors: Spencer, M K, Katz, A
• Format: Journal Article
• Language: English
• Published: United States 01.06.1991
• Subjects: Adenine Nucleotides - metabolism; Adult; Blood Glucose - metabolism; Citric Acid Cycle; Energy Metabolism; Female; Glycogen - metabolism; Glycolysis; Humans; Inosine Monophosphate - metabolism; Lactates - blood; Male; Muscles - metabolism; Muscles - physiology; Oxygen Consumption; Phosphocreatine - metabolism; Physical Exertion; Reference Values

The effect of prior glycogen depletion on glycolysis [flux through phosphofructokinase (PFK)] and inosine monophosphate (IMP) formation in human skeletal muscle has been investigated. Eight subjects cycled at a work load calculated to elicit 95% of maximal O2 uptake on two occasions, the first to fa...