A physico-chemical properties based model for estimating evaporation and absorption rates of perfumes from skin

• Published in: International journal of cosmetic science Vol. 23; no. 1; pp. 49 - 58
• Main Authors: Kasting, G.B., Saiyasombati, P.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.02.2001; Blackwell Science
• Subjects: absorption; Allergic diseases; Applied sciences; Biological and medical sciences; Chemical industry and chemicals; Essential oils, perfumes; evaporation; Exact sciences and technology; exposure assessment; fragrance; Immunopathology; mathematical model; Medical sciences; Skin allergic diseases. Stinging insect allergies; Washing products. Cosmetics and toiletries. Perfumes; Human; Terpenoid; Perfume; Alcohol; Evaporation; Aldehyde; Percutaneous route; Toxicokinetics; Absorption; Skin; Kinetics; Mathematical model; Physicochemical properties; Allergen

Synopsis Because of their potential for inducing allergic contact dermatitis (ACD) if used improperly, perfumes are carefully assessed for dermal safety prior to incorporation into cosmetic products. Exposure assessment for these materials often involves the conservative assumption of 100% absorptio...