Structural Basis for the Understanding of Entry Inhibitors against SARS Viruses

• Published in: Current medicinal chemistry Vol. 29; no. 4; p. 666
• Main Authors: Kushwaha, Prem Kumar, Kumari, Neha, Nayak, Sneha, Kishor, Keshav, Sharon, Ashoke
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.02.2022
• Subjects: COVID-19 - drug therapy; Humans; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus - chemistry; Spike Glycoprotein, Coronavirus - metabolism; Virus Internalization; COVID-19; receptor-binding domain(RBD); SARS-CoV2; protein-protein interface; Severe acute respiratory syndrome (SARS); entry inhibitors

Outbreaks due to Severe Acute Respiratory Syndrome-Corona virus 2 (SARSCoV- 2) initiated in Wuhan city, China, in December 2019 and continued to spread Internationally, posing a pandemic threat as declared by WHO and as of March 10, 2021, confirmed cases reached 118 million along with 2.6 million de...