The placental transfer of erythromycin in human pregnancies with group B streptococcal infection

• Published in: Ginekologia polska Vol. 86; no. 1; pp. 33 - 39
• Main Authors: Bulska, Magdalena, Szcześniak, Piotr, Pięta-Dolińska, Agnieszka, Oszukowski, Przemysław, Orszulak-Michalak, Daria
• Format: Journal Article
• Language: English
• Published: Poland Wydawnictwo Via Medica 2015
• Subjects: Anti-Infective Agents - administration & dosage; Antibiotic Prophylaxis; Antibiotics; Case-Control Studies; Erythromycin - administration & dosage; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases - prevention & control; Infections; Infectious Disease Transmission, Vertical - prevention & control; Injections, Intravenous; Maternal-Fetal Exchange; Placenta - drug effects; Pregnancy; Pregnancy Complications, Infectious - drug therapy; Pregnancy Complications, Infectious - microbiology; Prenatal exposure; Streptococcal Infections - drug therapy; Streptococcal Infections - microbiology; Streptococcus infections; Veins & arteries

The aim of this study was to investigate the effectiveness of erythromycin in preventing fetal and intrauterine group B streptococcal (GBS) infections. The study evaluated the penetration of erythromycin through the placenta, by comparing umbilical vein and maternal serum erythromycin concentrations...